Puerto Rico has declared a dengue epidemic with over 500 reported cases and more than 340 hospitalizations. The Centers for Disease Control and Prevention issued a travel warning for American travelers. Dengue fever poses a public health threat globally with symptoms like high fever and severe headaches. Countries like Brazil, India, the Philippines, Indonesia, and Thailand have reported high numbers of cases. Two vaccines, Dengvaxia and Dengue Tetravalent Vaccine, provide protection against all four dengue virus serotypes. Dengvaxia is FDA-approved for children 9 to 16, while Qdenga is available in several countries but not in the U.S.
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